Skip to content

Domain B: Data Semantics & Quality

Using the domain reference

Domain B includes the five maturity descriptors and the source-verified minimum evidence for L3–L5. Expand the evidence section beneath each indicator and retain an auditable assessment record. See How to Apply HDRL.

Focus: Standardisation, documentation, and quality assurance

Indicators: 6 (4 Core, 2 Enhancement)

The business question

Is the data messy or ready-to-use? High maturity slashes the time spent cleaning data.

Researchers consistently report that data preparation consumes 60–80% of project time. Organisations that invest in common data models, terminology mapping, and curated research-ready datasets dramatically reduce time-to-insight and improve reproducibility. This domain measures whether data is merely available or genuinely usable at scale.


Indicator Summary

ID Indicator Type Class Unit
B.1.1 Common Data Model Adoption Core C1 Both
B.1.2 Terminology Standards Core C1 Both
B.2.1 Quality Framework & Monitoring Core B0 Both
B.2.2 Data Documentation & Metadata Core B0 Both
B.3.1 Curated Dataset Availability Enhancement O Both
B.3.2 Phenotype Library & Validation Enhancement O Both

B.1 — Analytical Interoperability

B.1.1 Common Data Model Adoption

CORE · C1 · Both

Level Description
L1 No CDM. Data in source formats with bespoke schemas.
L2 CDM (OMOP, Sentinel, PCORnet, or equivalent) evaluated. Mapping assessed. Pilot planned.
L3 Core datasets partially mapped. Coverage <50%. CDM available but not routine.
L4 Core datasets mapped to recognised CDM with >= 60% coverage. CDM maintained and refreshed. Standard tools operational.
L5 Comprehensive CDM. Externally validated. Contributing to international networks. CDM-native services.
Minimum evidence for L3–L5

Use this source-defined minimum evidence with the maturity descriptors above. Record the artefact, date, scope and the claim it supports.

L3 minimum evidence

  • CDM selection and mapping approach documented (ETL plan, data model choice)
  • Evidence of partial mapping and use on core datasets (tables, coverage metrics, pilot analyses)

L4 minimum evidence

  • Mapping/ETL documentation + evidence >=60% coverage for core datasets (counts/metrics)
  • Operational CDM environment (repository, pipelines, refresh schedule) and maintained mappings
  • Evidence standard tools are available and used (e.g., OHDSI stack)

L5 minimum evidence

  • External validation/quality review of CDM mappings (peer review, audit, network validation)
  • Evidence CDM is comprehensive and routinely refreshed (change logs, release notes)
  • Evidence of contribution/participation in relevant networks (methods/tools shared, study participation)

B.1.2 Terminology Standards

CORE · C1 · Both

Level Description
L1 No consistent standards. Codes as recorded (mixture of Read, ICD-10, OPCS, local).
L2 Strategy defined. Target standards identified. Baseline assessed.
L3 Primary standards adopted (SNOMED CT, dm+d for new systems). Legacy retains original. Partial mapping.
L4 SNOMED CT, dm+d, ICD-10/OPCS consistently applied. Terminology services operational. Limitations documented.
L5 Full SNOMED CT with semantic interoperability. Advanced services. Contributing to standards.
Minimum evidence for L3–L5

Use this source-defined minimum evidence with the maturity descriptors above. Record the artefact, date, scope and the claim it supports.

L3 minimum evidence

  • Terminology standards strategy documented + mapping plan
  • Evidence of partial adoption/mapping on at least one major dataset/system

L4 minimum evidence

  • Evidence terminology standards are consistently applied (samples/audits across datasets)
  • Operational terminology service or controlled mapping process + documented limitations
  • Governance artefact for terminology updates/versioning

L5 minimum evidence

  • Evidence of semantic interoperability at scale (cross-system mapping quality, reduced local code use)
  • Advanced terminology services (e.g., value set management) with usage metrics
  • Contribution to national/international terminology work (submissions, participation)

B.2 — Data Quality

B.2.1 Quality Framework & Monitoring

CORE · B0 · Both

Level Description
L1 No framework. Issues ad-hoc. No monitoring.
L2 Framework defined. Dimensions identified. Baseline initiated.
L3 Metrics for core datasets. Annual reporting. Issues documented. Improvement underway.
L4 Comprehensive monitoring with automated checks. Metrics published. SLAs defined. Root cause analysis.
L5 Real-time monitoring. Benchmarked nationally/internationally. Certification or audit.
Minimum evidence for L3–L5

Use this source-defined minimum evidence with the maturity descriptors above. Record the artefact, date, scope and the claim it supports.

L3 minimum evidence

  • Quality framework documented with defined dimensions and responsibilities
  • Evidence of quality metrics produced for core datasets and issues tracked

L4 minimum evidence

  • Documented quality framework with automated checks + coverage across core datasets
  • Published/internal quality dashboard with metrics and thresholds
  • Evidence of root-cause analysis process and tracked remediation actions

L5 minimum evidence

  • Evidence of near-real-time or high-frequency monitoring for priority datasets
  • Benchmarking against external comparators (UK/international) or certification/audit
  • Evidence of continuous quality improvement (trend improvement over time)

B.2.2 Data Documentation & Metadata

CORE · B0 · Both

Level Description
L1 Minimal documentation. Tacit knowledge. No catalogue.
L2 Initiative underway. Basic documentation. Catalogue developing.
L3 Structured metadata for core datasets. Variable quality.
L4 Comprehensive, standardised metadata. Machine-readable. Searchable catalogue integrated with access. Regular updates.
L5 Rich ecosystem with automated generation. Provenance and lineage tracking. Community contributions.
Minimum evidence for L3–L5

Use this source-defined minimum evidence with the maturity descriptors above. Record the artefact, date, scope and the claim it supports.

L3 minimum evidence

  • Structured metadata exists for core datasets (data dictionary/metadata template) with variable completeness
  • Catalogue or register exists (even if partial) and is used for discovery

L4 minimum evidence

  • Standardised, machine-readable metadata for core datasets (schema, example records)
  • Searchable catalogue integrated with access workflow (screenshots/URL + process)
  • Evidence of regular metadata updates (change log, release cadence)

L5 minimum evidence

  • Automated metadata generation or validation pipeline (tooling evidence)
  • Lineage/provenance documentation (data flows, transformations) with traceability
  • Evidence of community contribution mechanism (issues/PRs, feedback loops)

B.3 — Research-Ready Data Products

B.3.1 Curated Dataset Availability

ENHANCEMENT · O · Both

Level Description
L1 No curated datasets. Raw extracts requiring extensive cleaning.
L2 Needs assessed. Priority datasets identified. Pilot underway.
L3 Selected curated datasets. Methodology documented but not standardised.
L4 Portfolio with standard methodology. Derived variables, phenotypes, linked data. Version control.
L5 Comprehensive library. Community contributions. Automated pipelines. Benchmarked.
Minimum evidence for L3–L5

Use this source-defined minimum evidence with the maturity descriptors above. Record the artefact, date, scope and the claim it supports.

L3 minimum evidence

  • Pilot curated datasets produced with documented methodology
  • Evidence curated outputs used in at least one project and are versioned at least minimally

L4 minimum evidence

  • Curated dataset portfolio list + published methodology/SOP
  • Version control evidence for curated products (release notes, tags)
  • Evidence curated datasets are routinely used (project examples/usage stats)

L5 minimum evidence

  • Evidence of comprehensive curated library with automated pipelines
  • Community contribution process with governance (requests, approvals, updates)
  • Benchmarking or external validation of curated products (comparisons, audits)

B.3.2 Phenotype Library & Validation

ENHANCEMENT · O · Both

Level Description
L1 No library. Researchers define from scratch.
L2 Concept established. Initial phenotypes documented. No validation.
L3 Growing library. Selected phenotypes validated. Searchable but not integrated.
L4 Comprehensive with validated definitions. Standardised validation. Integrated with access. Version control.
L5 Internationally validated. Cross-references HDR UK/OHDSI. Phenotype-as-code.
Minimum evidence for L3–L5

Use this source-defined minimum evidence with the maturity descriptors above. Record the artefact, date, scope and the claim it supports.

L3 minimum evidence

  • Initial phenotype library exists (definitions stored and discoverable)
  • Evidence of validation for selected phenotypes or documented validation plan

L4 minimum evidence

  • Phenotype library with validated definitions and versioning (repository + governance)
  • Standard validation protocol + evidence of completed validations
  • Integration evidence (library searchable and usable within analysis environments)

L5 minimum evidence

  • International validation/crosswalk evidence (e.g., OHDSI/HDR UK alignment) where relevant
  • Phenotype-as-code implementation (tests, CI, reproducible packages)
  • Evidence of sharing/contribution beyond the organisation (public repos, publications)